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As select ECM components are known to regulate specific stem-cell functions, a robust characterization of cell-derived ECM proteomic composition is critical to better comprehend the role of the ECM in directing cellular processes.
Here, we characterized and compared the protein composition of ECM produced in vitro bkology bone marrow-derived MSC, adipose-derived MSC and neonatal fibroblasts dating matrix biology names from different donors, employing quantitative proteomic methods.
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